Clinical Trial Keywords
Restless; Daytime Drowsiness; Restless Legs Syndrome
Selected Publications
1. Silver N, Allen RP, Senerth J, Earley CJ. A 10-year, 多巴胺激动剂和美沙酮治疗不宁腿综合征的纵向评价. Sleep Medicine. 2011 12(5):440-4.
2. 温克尔曼J, Czamara D, Schormair B, Knauf F, Schulte EC, Trenkwalder C,等. 全基因组关联研究发现2p14和16q12上新的不宁腿综合征易感位点.1. PLoS Genet. 2011;7(7):e1002171.
3. Edwards RR, Quartana PJ, Allen RP, Greenbaum S, Earley CJ, Smith MT. 不宁腿综合征治疗和未治疗患者疼痛反应的改变:与睡眠中断的关系. Sleep Medicine. 2011;12(6):603-9.
4. Earley CJ, Kuwabara H, Wong DF, Gamaldo C, Salas R, Brasic J, et al. 不宁腿综合征患者纹状体中多巴胺转运体减少. Sleep. 2011;34(3):341-7. PMCID: 3041710.
5. Connor JR, Ponnuru P, Wang X-S, Patton SM, Allen RP, Earley CJ. Profile of altered brain iron acquisition in restless legs syndrome. Brain. 2011;134(4):959-68. PMCID: 3069701.
6. Connor JR, Ponnuru P, Lee B-Y, Podskalny GD, Alam S, Allen RP, et al. 尸检和影像学分析显示不宁腿综合征的中枢神经系统髓鞘形成减少. Sleep Medicine. 2011;12(6):614-19.
7. Quiroz C, Pearson V, Gulyani S, Allen R, Earley C, Ferre S. 缺铁大鼠纹状体腺苷A(2A)受体上调:对运动和皮质纹状体神经传递的影响. Exp Neurol. 2010;224(1):292-8. PMCID: 2885550.
8. Pantaleo NP, Hening WA, Allen RP, Earley CJ. 妊娠是家族性RLS患病率性别差异的主要原因. Sleep Med. 2010;11:310-3. PMCID: 2830334.
9. Earley CJ, Silber MH. 不宁腿综合征:了解其后果和需要更好的治疗. Sleep Medicine. 2010;11(9):807-15.
10. Xiong L, Catoire H, Dion P, Gaspar C, Lafreniere RG, Girard SL, et al. 与不宁腿综合征相关的MEIS1内含子风险单倍型影响其mRNA和蛋白表达水平. Hum Mol Genet. 2009;18(6):1065-74. PMCID: 2722232.
11. Unger EL, Earley CJ, Beard JL. Diurnal cycle influences peripheral and brain iron levels in mice. J Appl Physiol. 2009;106:187-93. PMCID: 2636939.
12. Snyder AM, Wang X, Patton SM, Arosio P, Levi S, Earley CJ, et al. 不宁腿综合征黑质线粒体铁蛋白的研究. J Neuropathol Exp Neurol. 2009;68(11):1193-9. PMCID: 3024883.
13. Salas RE, Gamaldo CE, Allen RP, Earley CJ. 静源性夜间运动障碍:一种不宁腿综合征(RLS)变体或一种新的综合征? Sleep Med. 2009;10:396-7.
14. Hening WA, Allen RP, Washburn M, Lesage SR, Earley CJ. 不宁腿综合征的四种诊断标准不能排除混杂条件(“模仿”)。. Sleep Medicine. 2009;10(9):976-81. PMCID: 2766267.
15. Gulyani S, Earley CJ, Camandola S, Maudsley S, Ferr S, Mughal MR,等. 铁浓度降低可增加小鼠纹状体和培养的人神经母细胞瘤细胞中腺苷A2A受体的水平. Experimental Neurology. 2009;215(2):236-42. PMCID: 2784599.
16. Gamaldo C, Benbrook AR, Allen RP, Oguntimein O, Earley CJ. 评估不宁腿综合征(RLS)患者与睡眠受限对照组的日间警觉性. Sleep Medicine. 2009;10(1):134-8. PMCID: 2650846.
17. Earley CJ, Horska A, Mohamed MA, Barker PB, Beard JL, Allen RP. A randomized, double-blind, 静脉注射蔗糖铁治疗不宁腿综合征的安慰剂对照试验. Sleep Med. 2009;10(2):206-11. PMCID: 2703581.
18. Earley CJ, Allen RP, Connor JR, Ferrucci L, Troncoso J. RLS尸检脑组织A11系统多巴胺能神经元显示正常. Sleep Med. 2009;10(10):1155-7. PMCID: 2783651.
19. Earley CJ. The importance of oral iron therapy in restless legs syndrome. Sleep Medicine. 2009;10(9):945-6.
20. Connor JR, Wang XS, Allen RP, Beard JL, Wiesinger JA, Felt BT, et al. 不宁腿综合征中壳核和黑质多巴胺能谱的改变. Brain. 2009;132(Sep):2403-12. PMCID: 2732265.
21. Hening WA, Allen RP, Washburn M, Lesage S, Earley CJ. 不宁腿综合征的霍普金斯电话诊断访谈的验证. Sleep Medicine. 2008;9(3):283-9.
22. Gamaldo CE, Benbrook AR, Allen RP, Oguntimein O, Earley CJ. 对不宁腿综合征(RLS)相关认知缺陷的进一步评估. Sleep Medicine. 2008;9(5):500-5. PMCID: 2532669.
23. Earley CJ, Ponnuru P, Wang X, Patton SM, Conner JR, Beard JL, et al. 不宁腿综合征患者淋巴细胞铁代谢的改变. Sleep. 2008;31(6):847-52. PMCID: 2442411.
24. Cho YW, Shin WC, Yun CH, Hong SB, Kim JH, Allen RP, et al. Epidemiology of restless legs syndrome in Korean adults. Sleep. 2008;31(2):219-23. PMCID: 2225579.
25. Gamaldo CE, Benbrook AR, Allen RP, Scott JA, Henning WA, Earley CJ. 与不宁腿综合征(RLS)诊断相关的儿童和成人因素. Sleep Medicine. 2007;8(7-8):716-22.
26. Pearson VE, Allen RP, Dean T, Gamaldo CE, Lesage SR, Earley CJ. Cognitive deficits associated with restless legs syndrome (RLS). Sleep Med. 2006;7(1):25-30.
27. Earley CJ, Hyland K, Allen RP. 不宁腿综合征患者脑脊液多巴胺能测量的昼夜变化. Sleep Med. 2006;7(3):263-8.
28. Earley CJ, Barker PB, Horska A, Allen RP. 核磁共振成像测定早发性和晚发性不宁腿综合征患者脑铁浓度. Sleep Med. 2006;7:458-61.
29. Earley CJ, Allen RP. Restless legs syndrome augmentation associated with tramadol. Sleep Med. 2006;7(7):592-3.
30. Earley CJ, Heckler D, Allen RP. 反复静脉剂量的铁提供了有效的补充治疗不宁腿综合征. Sleep Med. 2005;6(4):301-5.
31. Earley CJ, Connor JR, Beard JL, Clardy SL, Allen RP. 脑脊液中铁蛋白水平与不宁腿综合征:不同临床表型的影响. Sleep. 2005;28(9):1069-75.
32. Earley CJ, Heckler D, Allen RP. 葡聚糖铁静脉注射治疗不宁腿综合征. Sleep Med. 2004;5(3):231-5.
33. Earley CJ. Clinical practice. Restless legs syndrome. N Engl J Med. 2003;348(21):2103-9.
34. Allen RP, La Buda MC, Becker P, Earley CJ. Family history study of the restless legs syndrome. Sleep Med. 2002;3(Suppl):S3-7.
35. Earley CJ, Hyland K, Allen RP. 不宁腿综合征患者的脑脊液多巴胺、血清素和生物蝶呤代谢物. Mov Disord. 2001;16(1):144-9.
36. Allen RP, Barker PB, Wehrl F, Song HK, Earley CJ. MRI measurement of brain iron in patients with restless legs syndrome. Neurology. 2001;56(2):263-5.
37. Earley CJ, Connor JR, Beard JL, Malecki EA, Epstein DK, Allen RP. 不宁腿综合征患者脑脊液铁蛋白和转铁蛋白浓度异常. Neurology. 2000;54(8):1698-700.
38. Earley CJ, Yaffee JB, Allen RP. 培高利特治疗不宁腿综合征的随机、双盲、安慰剂对照试验. Neurology. 1998;51(6):1599-602.
39. Allen RP, Earley CJ. Augmentation of the restless legs syndrome with carbidopa/levodopa. Sleep. 1996;19(3):205-13.
Patient Ratings & Comments
患者评分分数是通过Press Ganey对全国CG-CAHPS医疗实践患者体验调查中与医生相关问题的所有回答的平均值. 回答以1到5分进行衡量,5分是最高分. 我们还通过Press Ganey收集了CG-CAHPS医疗实践调查的评论,并将其完整地展示出来. Patients are de-identified for confidentiality and patient privacy.