The Johns Hopkins Myelitis and Myelopathy Center, formerly the Transverse Myelitis Center, was the first center in the U.S. 并致力于横贯脊髓炎的诊断、治疗和研究. 此后，我们扩大了我们的重点，以涵盖脊髓炎和脊髓病疾病的全谱. Our goal is to help patients maximize treatment, recovery and daily function, 当我们进行研究以更好地了解这些使人衰弱的疾病时.
Conditions We Treat
通过与约翰霍普金斯医学院的医生合作, 我们提供全面的诊断评估和症状管理:
- Transverse myelitis (特发性、代谢性、感染性和感染性后)
- Acute flaccid myelitis
- Compressive and spondylotic myelopathies
- Encephalomyelitis
- 髓鞘少突胶质细胞糖蛋白(MOG)抗体相关疾病(MOGAD)
- Neuromyelitis Optica Spectrum Disorder (NMOSD)
- Spinal cord strokes
- Vascular myelopathies
Expert Care for Patients with Myelopathies
约翰霍普金斯脊髓炎和脊髓病中心致力于将需要治疗的人与提供治疗的人联系起来.
Neurologic Care for Newly Diagnosed
我们帮助新诊断的患者，他们正在经历疾病的急性阶段，需要专家的神经学护理. 我们的团队还将与您一起制定长期症状管理计划.
Multi-Specialty Symptom Management
我们也帮助那些患有脊髓病一段时间的人，他们希望更好地控制症状，提高生活质量. 我们会帮你联系约翰·霍普金斯大学的康复专家, 疼痛医学和其他领域，将帮助你建立一个定制的护理计划.
Appointment Information
如果发生紧急情况，请拨打911和/或前往最近的医院. Otherwise, 请使用以下信息安排预约或将患者转介到约翰霍普金斯脊髓炎和脊髓病中心.
When you call 410-614-1522 to request an appointment at our center, 我们的呼叫中心工作人员会问您一些问题，并要求您发送相关的医疗记录. 请在致电前准备好以下资料:
- 急诊科和/或医院关于你的神经学诊断的记录.
- Clinic notes from neurological assessments.
- 化验结果包括血液化验和脑脊液化验.
- 脑和脊柱的核磁共振成像图像，血管造影. You can upload the digital images to AMBRA.
- 与您的诊断有关的其他重要临床文件.
- 全球十大外围足球平台，包括手机、家庭电话和电子邮件.
- Front and back of your insurance card.
If you do not have a confirmed diagnosis of myelopathy, 您将被转介到我们中心以外的普通神经科医生那里进行评估. 如果你的脊髓病诊断得到证实，我们将在我们的诊所见你.
2022年研究更新:多发性硬化症、脊髓炎和脊髓病以及视神经脊髓炎
我们中心对脊髓病进行了大量的研究, looking to improve diagnosis and treatment. Drs. Carlos Pardo, Ellen Mowry, Peter Calabresi和Shiv Saidha概述了横脊髓炎相关临床研究的新进展, multiple sclerosis and other myelopathies, 包括COVID-19对这些疾病患者的影响.
View our published researchOur Research Publications
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- MOG抗体疾病的亚临床疾病活动性和进展性疾病的证据 . Molazadeh N, Filippatou AG, Vasileiou ES, Levy M, Sotirchos ES. J Neuroimmunol. 2021 Nov 15;360:577702. doi: 10.1016/j.jneuroim.202577702. Epub 2021 Aug 26.
- 视神经炎-视神经脊髓炎中的非依赖性视网膜萎缩. Filippatou AG, Vasileiou ES, He Y, Fitzgerald KC, Kalaitzidis G, Lambe J, Mealy MA, Levy M, Liu Y, Prince JL, Mowry EM, Saidha S, Calabresi PA, Sotirchos ES. J Neuroophthalmol. 2021 May 17. doi: 10.1097/WNO.000000000000128
- 视神经脊髓炎视网膜形态学异常的体内鉴定. Sotirchos ES, Saidha S, Byraiah G, Mealy MA, Ibrahim MA, Sepah YJ, Newsome SD, Ratchford JN, Frohman EM, Balcer LJ, Crainiceanu CM, Nguyen QD, Levy M, Calabresi PA. Neurology. 2013 Apr 9;80(15):1406-14. doi: 10.1212/WNL.0b013e31828c2f7a. Epub 2013 Mar 20.
- AQP4-IgG and MOG-IgG Related Optic Neuritis-Prevalence, Optical Coherence Tomography Findings, 视觉结果:系统回顾和荟萃分析. Filippatou AG, Mukharesh L, Saidha S, Calabresi PA, Sotirchos ES. Front Neurol. 2020 Oct 8;11:540156. doi: 10.3389/fneur.2020.540156. eCollection 2020.
- 与MOG-IgG血清阳性和多发性硬化症相比，水通道蛋白-4 IgG血清阳性与视神经炎后较差的视力预后相关, independent of macular ganglion cell layer thinning. Sotirchos ES, Filippatou A, Fitzgerald KC, Salama S, Pardo S, Wang J, Ogbuokiri E, Cowley NJ, Pellegrini N, Murphy OC, Mealy MA, Prince JL, Levy M, Calabresi PA, Saidha S. Mult Scler. 2020 Oct;26(11):1360-1371. doi: 10.1177/1352458519864928. Epub 2019 Jul 31.
- AQP4-IgG血清阳性NMOSD的亚临床定量视网膜层异常证据. Filippatou AG, Vasileiou ES, He Y, Fitzgerald KC, Kalaitzidis G, Lambe J, Mealy MA, Levy M, Liu Y, Prince JL, Mowry EM, Saidha S, Calabresi PA, Sotirchos ES. Mult Scler. 2021 Oct;27(11):1738-1748. doi: 10.1177/1352458520977771. Epub 2020 Dec 14.
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- 急性弛缓性脊髓炎:病因、诊断和治疗. Murphy OC, Messacar K, Benson L, Bove R, Carpenter JL, Crawford T, Dean J, DeBiasi R, Desai J, Elrick MJ, Farias-Moeller R, Gombolay GY, Greenberg B, Harmelink M, Hong S, Hopkins SE, Oleszek J, Otten C, Sadowsky CL, Schreiner TL, Thakur KT, Van Haren K, Carballo CM, Chong PF, Fall A, Gowda VK, Helfferich J, Kira R, Lim M, Lopez EL, Wells EM, Yeh EA, Pardo CA; AFM working group. Lancet. 2021 Jan 23;397(10271):334-346. doi: 10.1016/S0140-6736(20)32723-9. Epub 2020 Dec 23. PMID: 33357469; PMCID: PMC7909727.
- Acute Flaccid Myelitis: A Clinical Review. Murphy OC, Pardo CA. Semin Neurol. 2020 Apr;40(2):211-218. doi: 10.1055/s-0040-1705123. Epub 2020 Mar 6. PMID: 32143233.
- Comparative quantitative clinical, neuroimaging, 急性弛缓性脊髓炎患儿在急性期和恢复期的功能特征. Gordon-Lipkin E, Muñoz LS, Klein JL, Dean J, Izbudak I, Pardo CA. Dev Med Child Neurol. 2019 Mar;61(3):366-375. doi: 10.1111/dmcn.14030. Epub 2018 Sep 17. PMID: 30225922.
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- 神经结节病的诊断标准:来自神经结节病协会共识组. Stern BJ, Royal W 3rd, Gelfand JM, Clifford DB, Tavee J, Pawate S, Berger JR, Aksamit AJ, Krumholz A, Pardo CA, Moller DR, Judson MA, Drent M, Baughman RP. Definition and Consensus JAMA Neurol. 2018 Dec 1;75(12):1546-1553. doi: 10.1001/jamaneurol.2018.2295. PMID: 30167654.
- 结节病相关脊髓病的临床和MRI表型. Murphy OC, Salazar-Camelo A, Jimenez JA, Barreras P, Reyes MI, Garcia MA, Moller DR, Chen ES, Pardo CA. Neurol Neuroimmunol Neuroinflamm. 2020 Apr 8;7(4):e72 doi: 10.1212/NXI.0000000000000722. PMID: 32269072; PMCID: PMC7176244.
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- 横贯脊髓炎:发病机制、诊断与治疗. Krishnan C, Kaplin AI, Deshpande DM, Pardo CA, Kerr DA. Front Biosci. 2004 May 1;9:1483-99. doi: 10.2741/135 PMID: 14977560.
- 临床生物标志物区分脊髓炎与血管性和其他原因的脊髓病. Barreras P, Fitzgerald KC, Mealy MA, Jimenez JA, Becker D, Newsome SD, Levy M, Gailloud P, Pardo CA. Neurology. 2018 Jan 2;90(1):e12-e21. doi: 10.1212/WNL.0000000000004765. Epub 2017 Dec 1. PMID: 29196574; PMCID: PMC5754646.
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- MOGAD:它与其他神经炎性疾病的区别和相似之处. Shahriari M, Sotirchos ES, Newsome SD, Yousem DM. AJR Am J Roentgenol. 2021 Apr;216(4):1031-1039. doi: 10.2214/AJR.20.2406 Epub 2021 Feb 17.
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- 脊髓病检查期间通过增强计算机断层扫描记录的脊髓瘘:一个失去的机会. Hedjoudje A, Murphy OC, Gregg L, Pardo CA, Gailloud P. Neuroradiology. 2021 Feb;63(2):201-207. doi: 10.1007/s00234-020-02601-x. Epub 2020 Nov 16. PMID: 33196864.
- 18例脊髓血管畸形患者30张误报正常的血管造影分析. Barreras P, Heck D, Greenberg B, Wolinsky JP, Pardo CA, Gailloud P. AJNR Am J Neuroradiol. 2017 Sep;38(9):1814-1819. doi: 10.3174/ajnr.A5275. Epub 2017 Jul 20. PMID: 28729296; PMCID: PMC7963703.